Four pillars of heart failure: contemporary ... - Open Heart
Mar 2, 2021 · The past two decades have heralded dramatic improvements in outcomes for people living with heart failure with reduced ejection fraction (HFrEF). 1 The more widespread implementation of disease modifying pharmacological therapies,2 supported by landmark trials of renin-angiotensin system inhibitors3 and beta-blockers4 have improved longevity despite a background of an ageing and increasingly ...
Homepage | Open Heart
Open Heart is dedicated to publishing high quality, peer reviewed medical research in all disciplines and therapeutic areas of cardiovascular medicine. Research is published across all study phases and designs, from protocols to phase I trials to meta-analyses, including small or specialist studies. Opinionated discussions on controversial ...
Myo-inositol for insulin resistance, metabolic syndrome, polycystic ...
Mar 1, 2022 · Myo-inositol, also known as inositol (cyclohexanehexol), is a cyclic carbohydrate with six hydroxyl groups.1 For a long time, it was considered a B vitamin (vitamin B8). However, it is not considered an essential nutrient because it is formed from glucose. Each kidney makes around 2 g of myo-inositol per day, and the average dietary intake is 0.5–1.0 g/day.2 3 The liver and brain also ...
Vitamin K2—a neglected player in cardiovascular health: a …
Nov 15, 2021 · Vitamin K2 serves an important role in cardiovascular health through regulation of calcium homeostasis. Its effects on the cardiovascular system are mediated through activation of the anti-calcific protein known as matrix Gla protein. In its inactive form, this protein is associated with various markers of cardiovascular disease including increased arterial …
Contemporary characteristics, outcomes and novel risk score for ...
Background Takotsubo cardiomyopathy (TC) is an established differential diagnosis of myocardial infarction with non-obstructive coronaries with significant interest but limited data on prognostication. We reviewed the characteristics and in-hospital outcomes and developed a novel risk score for TC.Methods Using the National Inpatient Sample data from 2016 to 2020, we identified adult patients ...
Echocardiographic diagnosis of right-to-left shunt using ...
Aug 6, 2020 · Introduction. Patent foramen ovale (PFO) is a common finding with a prevalence of about 25% in the general population.1 A strong association between PFO and ischaemic stroke has been reported.2 Pulmonary arteriovenous malformation (PAVM) is a rare disease in the general population and causes a permanent right-to-left shunt (RLS).3 The association of pulmonary RLS grade on contrast ...
Current Issue | Open Heart
Tove Elizabeth Frances Hunt, Gunn Marit Traaen, Lars Aakerøy, Richard John Massey, Christina Bendz, Britt Øverland, Harriet Akre, Sigurd Steinshamn, Jan Pål Loennechen, Kaspar Broch, Thomas Helle-Valle, Øyvind Haugen Lie, Anne Kristine Anstensrud, Kristina H Haugaa, Lars Gullestad, Ole-Gunnar Anfinsen, Svend Aakhus.
Celebrating motherhood after Fontan operation: a difficult and …
Oct 9, 2024 · For women who had a Fontan operation, the prospect of a successful pregnancy remains a challenging and often distant goal. The survival of children with single ventricle physiology has been bleak until the development of innovative surgical procedures that improved the survival to adulthood. In 1958, William Glenn performed the Glenn surgery, a ...
Gold standard for diagnosing and treating chronic ischaemic …
Oct 8, 2024 · Diagnostic accuracy of invasive and non-invasive testing. The study by Bråtena et al1 showed that the accuracy, sensitivity and specificity of dobutamine stress echocardiography (DSE) were 61%, 43% and 75% against fractional flow reserve (FFR) and 64%, 46% and 74% against instantaneous wave-free ratio (iFR) in 102 patients with positive coronary CT angiography (CCTA), with low to medium ...
Harnessing the power of clinical decision support systems: …
Nov 28, 2023 · Clinical decision support systems (CDSSs) are increasingly integrated into healthcare settings to improve patient outcomes, reduce medical errors and enhance clinical efficiency by providing clinicians with evidence-based recommendations at the point of care. However, the adoption and optimisation of these systems remain a challenge. This review aims to provide an overview of the current state ...