Background Despite biomarker-guided initiation, non- or loss of response to biologic therapy occurs in a minority of patients with severe asthma. In cases of treatment failure, it is important to ...
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Background Development of emphysema and vascular stiffness in chronic obstructive pulmonary disease (COPD) may be due to a common mechanism of susceptibility to pulmonary and systemic elastin ...
Air Travel Working Party: Dr R K Coker (chair), Dr D A R Boldy, Dr R Buchdahl, Mr D Cramer, Professor D Denison, Wing Commander D P Gradwell, Professor J M B Hughes, Dr J A Innes, Dr A O C Johnson, Dr ...
Pulmonary Rehabilitation Research Group, Department of Respiratory Medicine and Thoracic Surgery, Glenfield Hospital, University Hospitals of Leicester NHS Trust, Leicester, UK Background: The ...
The pathophysiology of residual sleepiness in treated obstructive sleep apnoea (OSA) remains poorly understood. Animal models ...
Associations of pulmonary microvascular blood volume with per cent emphysema and CT emphysema subtypes in the community: the MESA Lung study ...
Background The Global Obstructive Lung Disease (GOLD) 2011 revision recommends the multidimensional assessment of COPD including comorbidities and has developed a ...
In this cohort study involving 9399 current and former smokers from the Genetic Epidemiology of Chronic Obstructive Pulmonary Disease study, we assessed the relationship between artificial ...
1 Department of Palliative Medicine, Royal Marsden and Royal Brompton NHS Foundation Trusts, London, UK 2 Department of Palliative Care, Policy and Rehabilitation, King's College London, Cicely ...
In a prospective study of 13 patients requiring pneumonectomy for unilateral post-tuberculous lung destruction the left side was found to be affected in 12. Review of a further 172 cases showed the ...
Introduction: Lung function impairment may be a risk factor for cardiovascular disease (CVD) events. Objective: To determine the relationship between the severity of airflow obstruction based on ...