Ranking all 32 teams using advanced analytics results in seven of the top 11 teams being from the AFC, while nine of the bottom 13 are also from the AFC. It's a conference of extremes, and here's how its teams stack up entering Week 13.

The Buffalo Bills (9-2) are riding high these days as they head into Week 13 of the NFL season coming off a bye while also being able to wrap up their division early. Buffalo is definitely focused on its upcoming matchup against the San Francisco 49ers (5-6),

The Buffalo Bills may have something extra to be thankful for on Thursday. Buffalo could be a win away from a fifth straight title in the AFC East shortly after the Thanksgiving feast. The Bills can clinch the division in Week 13 if the Miami Dolphins lose to the Green Bay Packers at Lambeau Field on Thursday Night Football and Buffalo defeats the San Francisco 49ers at Highmark Stadium on Sunday Night Football.

Brock Purdy remained limited in a Thanksgiving Day practice, keeping his status in doubt for the 49ers’ game Sunday at Buffalo. Purdy missed last Sunday’s 38-10 loss at Green Bay because of a shoulder injury that’s impaired his throwing ability since the previous game’s loss to Seattle.

The San Francisco 49ers are reeling and now head to Buffalo for a prime time game. Will they have their starting QB back in the fold?

The 49ers are welcoming Brock Purdy back to practice today after shoulder soreness kept him out of Sunday’s loss at Green Bay.