Los Angeles Rams coach Sean McVay is "not sad" he doesn't have to game plan for San Francisco 49ers stars Deebo Samuel and ...

Greg Papa joins "49ers Talk" host Matt Maiocco and discusses if 49ers wide receiver Brandon Aiyuk will step up in Rams ...

As the San Francisco 49ers set their sights on another deep playoff run this season, wide receiver Deebo Samuel is making one ...

Samuel (calf) won't practice Thursday, Jennifer Lee Chan of NBC Sports Bay Area reports.

The San Francisco 49ers will be missing two of their biggest playmakers when they visit SoFi Stadium on Sunday to face the ...

San Francisco 49ers' Deebo Samuel has emphasized that it’s now or never for their Super Bowl dreams. The team is under ...

Now comes the hard part for Kyle Shanahan — devising a game plan without Deebo Samuel and Christian McCaffrey.

Just two games into the season, the Rams (0-2) are approaching desperate times as they prepare to face the San Francisco ...

Despite grappling with injuries to key players like Deebo Samuel and Christian McCaffrey, the 49ers are set to demonstrate ...

George Kittle was not in attendance for Thursday's practice session. According to ESPN's Adam Schefter, Kittle is experiencing tightness in ...

The Niners are lost All-Pro running back Christian McCaffrey and star receiver Deebo Samuel to injuries before Kittle ...

George Kittle and Charvarius Ward both missed practice Thursday, three days shy of the 49ers’ visit to Los Angeles where they ...