Brandon Aiyuk caught four passes for 43 yards in the San Francisco 49ers' Week 2 loss to the Minnesota Vikings. While it may not have been the ...

Greg Papa joins "49ers Talk" host Matt Maiocco and discusses if 49ers wide receiver Brandon Aiyuk will step up in Rams ...

Just two games into the season, the Rams (0-2) are approaching desperate times as they prepare to face the San Francisco ...

Defensive coordinator Nick Sorensen and run game coordinator and offensive line coach Chris Foerster reviewed the 49ers ...

The Niners are lost All-Pro running back Christian McCaffrey and star receiver Deebo Samuel to injuries before Kittle ...

The San Francisco 49ers will be without a couple of key players Sunday, but their troubles pale in comparison with the ...

The Los Angeles Rams host the San Francisco 49ers on Sunday as both NFC West rivals try to shake off dismal Week 2 ...

San Francisco 49ers wide receiver George Kittle received a notable practice update on Thursday ahead of Week 3's Rams matchup ...

Both the San Francisco 49ers and Los Angeles Rams are in danger of running out skeleton crews on Sunday due to injury ...

A strong fan presence can profoundly influence the outcome of a game, particularly in a venue like SoFi Stadium, where the ...

Los Angeles also won the teams' most recent matchup in Week 18 last season, with Carson Wentz leading the Rams past Sam ...