Benzoyl peroxide has antibacterial activity. Topical antibiotics available for treating acne include clindamycin (1% gel, lotion, solution, or pledgets applied b.i.d.), erythromycin (2% gel ...

Clindamycin and erythromycin inhibit protein synthesis by irreversibly binding to the ribosomal 50S subunit of P. acnes (Physician's Desk Reference, 2001). Whereas erythromycin is bactericidal ...