Data are needed on the effect of oxygen delivered through a high-flow nasal cannula, as compared with standard oxygen therapy, on intubation and mortality in patients with acute hypoxemic ...

Whole-blood transfusion has recently gained favor in the management of severe hemorrhage; however, data from large clinical trials evaluating its clinical effectiveness and safety are lacking. We ...

Untreated atrial fibrillation carries an approximately 3 to 5% annual risk of ischemic stroke. Long-term oral anticoagulation therapy decreases this risk to 1.7% with warfarin and to 1.5% with ...

Some foreign pharmaceutical plants that export generic drugs to the United States have glaring quality problems that can lead to drug shortages. There is a better way to assure the safety of ...

In patients with refractory systemic lupus erythematosus, in vivo generation of CD19 CAR T cells by means of lipid nanoparticles led to B-cell depletion, reduced disease activity, and no major toxi ...

Explore this issue of The New England Journal of Medicine (Vol. 390 No. 3).

Explore this issue of The New England Journal of Medicine (Vol. 393 No. 23).

Sotorasib plus Panitumumab in Refractory Colorectal Cancer with Mutated KRAS G12C (N Engl J Med 2023;389:2125-2139). As a result of late data entry, a reanalysis using a later data snapshot (March ...

Explore this issue of The New England Journal of Medicine (Vol. 392 No. 5).

To the Editor: Sanyal et al. (Oct. 21 issue)1 add important new data to our understanding of the natural course of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis (NASH). A substa ...

The CMS Innovation Center is approaching the next negotiation cycle for the CGT Access Model. Several considerations will guide the selection of future candidate diseases and potential new model ...

To the Editor: Morin and Buysse (July 18 issue) 1 provide a comprehensive overview of current assessments and treatments for insomnia. Their emphasis on cognitive behavioral therapy for insomnia as a ...