Nucleic acids may be labeled at their 3’ end, 5’ end, or throughout the molecule, depending on the desired application. Myriad of enzymatic or chemical methods are utilized to generate nucleic acids ...

A plethora of chemical or enzymatic methods are available to generate nucleic acids such as those labeled with fluorophores, enzymes and radioactive phosphates, or nucleotides modified with ...

A protocol is described for the incorporation of nitroxide spin-labels into specific 2′-sites within nucleic acids. This labeling strategy facilitates the investigation of nucleic acid structure and ...

The ability to label nucleic acids with a variety of tagged molecules has led to astonishing advances in molecular biology. Labeled DNA, RNA, and oligonucleotide probes have made possible techniques ...

Biotinylated nucleotides have emerged as a powerful tool in molecular biology, enabling researchers to explore genetic materials with unprecedented precision and sensitivity. These modified ...