Mutations in 3 genes (SPG4, SPG3, and SPG31) are implicated in one half of the autosomal dominant hereditary spastic paraplegias, which are part of the larger group of hereditary spastic diplegias ...

Hereditary Spastic Paraplegia (HSP) encompasses a heterogeneous group of genetic neurodegenerative disorders primarily characterised by progressive lower-limb spasticity and weakness. The condition ...

Hereditary spastic paraplegia (HSP) comprises a heterogeneous group of neurodegenerative disorders that are mainly characterised by progressive spasticity and weakness of the lower limbs. Recent ...

Mike Wolanin | The Republic Kyle Alumbaugh demonstrates how he uses his wheelchair ramp participate in 5k run, walk or roll to raise awareness for Hereditary Spastic Paraplegia and Primary Lateral ...

A disease-causing gene in hereditary spastic paraplegia bolsters the theory of altered lipid processing as a shared cause in motor neuron diseases. Genetic and cellular studies, led by Andrew Crosby ...

HOUSTON -- (Oct. 8, 2012) -- Rice University biochemist James McNew has gotten used to doing research on the fly, but he no longer has to do it on a shoestring thanks to a new grant from the National ...

Researchers from the University of Seville and the Seville Institute of Biomedicine (IBiS), in collaboration with the University of Cambridge, have identified a new role for one of the genes related ...

Scientists at the Montreal Neurological Institute and Hospital (MNI) have identified novel gene mutations that cause hereditary spastic paraplegia (HSP), a step forward in efforts to treat this ...

NASHVILLE, Tenn. (WKRN) – Imagine losing the strength in the muscles of your legs and not knowing why. The condition is often misdiagnosed and worsens with time. It’s a rare reality for about 20,000 ...

"Hereditary Spastic Paraplegias Market Insights, Epidemiology, and Market Forecast-2032"The hereditary spastic paraplegias treatment market is poised for significant expansion over the coming years, ...

University of Wisconsin–Madison researchers targeting a group of hereditary neurodegenerative diseases have found success using a gene therapy treatment in an animal model. The approach, which uses ...