Arsenal take on potential title rivals Manchester City in what could be a key clash at the Etihad Stadium this weekend and Mikel Arteta has been hard at work preparing for the game

All eyes will be on the Etihad Stadium come Sunday when the top two go head-to-head. Injuries to Kevin De Bruyne and Martin Odegaard mean neither side will be at full-strength, but Arsenal, particularly, cannot afford a defeat given they are already trailing the champions by two points.

Get exclusive match odds tips from Alan Shearer as the Betfair Ambassador gives his Premier League predictions for Matchday 4 - Saturday 21 September to Sunday 22 September

The Premier League returns this week following a busy midweek of European and Carabao Cup action. Manchester City welcome Arsenal in the game of the week. Crystal Palace host Manchester United and Liverpool will be looking to return to winning always against Bournemouth.

There is no doubt all eyes will fall on the Etihad Stadium this Sunday when Manchester City and Arsenal go head-to-head in the Premier League. City pipped Arsenal to the title last season, and this clash,

This weekend could have huge ramifications for the Premier League title race come the end of the season, with reigning champions Manchester City hosting last term's runners-up Arsenal.Both league

Tottenham Hotspur is in need of three points this weekend in a London derby against Brentford. Ange Postecoglou's team came up short in its last Premier League outing in the north London derby against rivals Arsenal.